L -Phenylalanine : an Organ Specific, Stereo-specific Inhibitor of Human Intestinal Alkaline Phosphatase

HUMAN alkaline phosphatase of intestine but not of liver, bile, bone, lung, kidney and spleen is almost completely (78 per cent) inhibited by L -phenylalanine and is not so affected by D -phenylalanine.

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Bibliographic Details
Published in:Nature (London) 1963-05, Vol.198 (4881), p.685-686
Main Authors: FISHMAN, WILLIAM H, GREEN, SIDNEY, INGLIS, NORMA I
Format: Article
Language:English
Subjects:
Humanities and Social Sciences
letter
multidisciplinary
Science
Science (multidisciplinary)
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Description
Summary:HUMAN alkaline phosphatase of intestine but not of liver, bile, bone, lung, kidney and spleen is almost completely (78 per cent) inhibited by L -phenylalanine and is not so affected by D -phenylalanine.
ISSN:0028-0836
1476-4687
DOI:10.1038/198685b0