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Antitumour Activity of N -Hydroxyurethane
N -HYDROXYURETHANE is known to be a carcinogen and to induce certain chromosomal aberrations 1,2 . It contains the hydroxamic acid group, a moiety apparently essential for the antitumour activity of hydroxyurea and its congeners 3,4 . For this reason, it was considered of interest to determine wheth...
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Published in: | Nature (London) 1966-08, Vol.211 (5052), p.984-985 |
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container_end_page | 985 |
container_issue | 5052 |
container_start_page | 984 |
container_title | Nature (London) |
container_volume | 211 |
creator | HAHN, MARY ANNE BOTKIN, CONSTANCE C ADAMSON, RICHARD H |
description | N
-HYDROXYURETHANE
is known to be a carcinogen and to induce certain chromosomal aberrations
1,2
. It contains the hydroxamic acid group, a moiety apparently essential for the antitumour activity of hydroxyurea
and its congeners
3,4
. For this reason, it was considered of interest to determine whether
N
-hydroxyurethane was active against various transplantable mouse tumours. |
doi_str_mv | 10.1038/211984a0 |
format | article |
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-HYDROXYURETHANE
is known to be a carcinogen and to induce certain chromosomal aberrations
1,2
. It contains the hydroxamic acid group, a moiety apparently essential for the antitumour activity of hydroxyurea
and its congeners
3,4
. For this reason, it was considered of interest to determine whether
N
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-HYDROXYURETHANE
is known to be a carcinogen and to induce certain chromosomal aberrations
1,2
. It contains the hydroxamic acid group, a moiety apparently essential for the antitumour activity of hydroxyurea
and its congeners
3,4
. For this reason, it was considered of interest to determine whether
N
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-HYDROXYURETHANE
is known to be a carcinogen and to induce certain chromosomal aberrations
1,2
. It contains the hydroxamic acid group, a moiety apparently essential for the antitumour activity of hydroxyurea
and its congeners
3,4
. For this reason, it was considered of interest to determine whether
N
-hydroxyurethane was active against various transplantable mouse tumours.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>5968317</pmid><doi>10.1038/211984a0</doi><tpages>2</tpages></addata></record> |
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issn | 0028-0836 1476-4687 |
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source | Nature.com |
subjects | Animals Humanities and Social Sciences letter Leukemia L1210 Leukemia, Experimental Mast Cells Mice multidisciplinary Neoplasms, Experimental Plasmacytoma Science Science (multidisciplinary) Urethane - pharmacology |
title | Antitumour Activity of N -Hydroxyurethane |
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