Method for estimating the Number of Eggs laid by Xenopus laevis in Response to the Injection of Gonadotrophin

OVULATION in Xenopus laevis can be induced by injecting human chorionic gonadotrophin (HCG); this procedure has been used to diagnose pregnancy 1,2 , or for the biological assay of HCG. Either the proportion of animals ovulating in a group, or the number of eggs laid by each individual, may form the...

Full description

Saved in:
Bibliographic Details
Published in:Nature (London) 1967-01, Vol.214 (5090), p.827-828
Main Authors: BARR, W. A., HOBSON, B. M., DI VITA, G.
Format: Article
Language:English
Subjects:
Humanities and Social Sciences
letter
multidisciplinary
Science
Science (multidisciplinary)
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:OVULATION in Xenopus laevis can be induced by injecting human chorionic gonadotrophin (HCG); this procedure has been used to diagnose pregnancy 1,2 , or for the biological assay of HCG. Either the proportion of animals ovulating in a group, or the number of eggs laid by each individual, may form the basis of a test 3–5 . A dose of 90 international units (IU) of HCG causes ovulation in most Xenopus , although there is a considerable variation in the number of eggs laid by each individual, from a few tens to several thousands. A method to estimate the number of eggs laid is described here.
ISSN:0028-0836
1476-4687
DOI:10.1038/214827a0