Method for estimating the Number of Eggs laid by Xenopus laevis in Response to the Injection of Gonadotrophin

OVULATION in Xenopus laevis can be induced by injecting human chorionic gonadotrophin (HCG); this procedure has been used to diagnose pregnancy 1,2 , or for the biological assay of HCG. Either the proportion of animals ovulating in a group, or the number of eggs laid by each individual, may form the...

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Published in:Nature (London) 1967-01, Vol.214 (5090), p.827-828
Main Authors: BARR, W. A., HOBSON, B. M., DI VITA, G.
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Language:English
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description OVULATION in Xenopus laevis can be induced by injecting human chorionic gonadotrophin (HCG); this procedure has been used to diagnose pregnancy 1,2 , or for the biological assay of HCG. Either the proportion of animals ovulating in a group, or the number of eggs laid by each individual, may form the basis of a test 3–5 . A dose of 90 international units (IU) of HCG causes ovulation in most Xenopus , although there is a considerable variation in the number of eggs laid by each individual, from a few tens to several thousands. A method to estimate the number of eggs laid is described here.
doi_str_mv 10.1038/214827a0
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Science
Science (multidisciplinary)
title Method for estimating the Number of Eggs laid by Xenopus laevis in Response to the Injection of Gonadotrophin
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