Induced Dominant Lethality in Mice by Phosphorus-32

DESPITE much work on the induction of mutations in mice by ionizing radiations 1 and chemicals 2–6 , the possible mutagenic effects of internally administered radioisotopes have received little attention (see, however, ref. 7). Any genetic effects of radioisotopes are important from the point of vie...

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Bibliographic Details
Published in:Nature (London) 1968-04, Vol.218 (5138), p.283-284
Main Authors: REDDI, O. S., VASUDEVAN, B.
Format: Article
Language:English
Subjects:
Animals
Female
Fertility - radiation effects
Fetal Death - radiation effects
Humanities and Social Sciences
Infertility
letter
Male
Mice
multidisciplinary
Phosphorus Isotopes
Pregnancy
Radiation Effects
Radiation Genetics
Science
Science (multidisciplinary)
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Summary:DESPITE much work on the induction of mutations in mice by ionizing radiations 1 and chemicals 2–6 , the possible mutagenic effects of internally administered radioisotopes have received little attention (see, however, ref. 7). Any genetic effects of radioisotopes are important from the point of view both of the hazards of radioactive fallout and of the use of certain isotopes in human medicine. We present here the results of preliminary observations of the effects of phosphorus-32 in work concerned with the evaluation of genetic hazards of certain important radio-nuclides in mice. Phosphorus-32 is known to produce mutations in Drosophila 8 and in micro-organisms 9 .
ISSN:0028-0836
1476-4687
DOI:10.1038/218283a0