Isolation and Biological Activity of a Microbial Conversion Product of Aflatoxin B1

ONE of the most striking and significant developments in synthetic chemistry has been the use of biological systems to achieve chemical transformations, especially the oxidation-reduction of steroids and alkaloids. Based on an analogous biological system, we have attempted to transform aflatoxin B 1...

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Bibliographic Details
Published in:Nature (London) 1968-08, Vol.219 (5157), p.967-967
Main Authors: DETROY, R. W., HESSELTINE, C. W.
Format: Article
Language:English
Subjects:
Humanities and Social Sciences
letter
multidisciplinary
Science
Science (multidisciplinary)
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Summary:ONE of the most striking and significant developments in synthetic chemistry has been the use of biological systems to achieve chemical transformations, especially the oxidation-reduction of steroids and alkaloids. Based on an analogous biological system, we have attempted to transform aflatoxin B 1 , a toxic secondary metabolite of Aspergillus flavus , by employing a known steroid-hydroxylating micro-organism.
ISSN:0028-0836
1476-4687
DOI:10.1038/219967a0