Uterine, Vaginal and Mammary Tumours induced by Nitrosoureas in Pregnant Rats

A NUMBER of nitroso compounds have high carcinogenic activity. Some of them selectively induce tumours at various sites such as the alimentary tract, respiratory, nervous and urinary systems 1,2 . The influence of changes in the general condition of the organism as well as in the functional activity...

Full description

Saved in:
Bibliographic Details
Published in:Nature (London) 1969-06, Vol.222 (5198), p.1064-1065
Main Author: ALEXANDROV, V. A.
Format: Article
Language:English
Subjects:
Animals
Female
Humanities and Social Sciences
Injections, Intraperitoneal
Injections, Intravenous
letter
Mammary Neoplasms, Experimental - chemically induced
multidisciplinary
Nitroso Compounds
Pregnancy
Pregnancy, Animal
Rats
Science
Science (multidisciplinary)
Urea
Uterine Neoplasms - chemically induced
Vaginal Neoplasms - chemically induced
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A NUMBER of nitroso compounds have high carcinogenic activity. Some of them selectively induce tumours at various sites such as the alimentary tract, respiratory, nervous and urinary systems 1,2 . The influence of changes in the general condition of the organism as well as in the functional activity of specific organs on the pattern of carcinogenesis is virtually unexplored. We report here on a peculiar shift in the organotropic carcinogenic effect of two alkylnitrosoureas in pregnant rats observed during 80 weeks after treatment.
ISSN:0028-0836
1476-4687
DOI:10.1038/2221064a0