Loading…
Automatically optimized vectorcardiographic features are associated with recurrence of atrial fibrillation after electrical cardioversion
Electrical cardioversion presents one of the treatment options for atrial fibrillation (AF). However, the early recurrence rate is high, reaching ~40% three months after the procedure. Features based on vectorcardiographic signals were explored to find association with early recurrence of AF. Eighty...
Saved in:
Published in: | Scientific reports 2025-01, Vol.15 (1), p.1257, Article 1257 |
---|---|
Main Authors: | , , , , , , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | |
---|---|
cites | cdi_FETCH-LOGICAL-c2274-414058dadb87211278da1085b779e994e7e7d7f3fa8b3bd5b51fd54b40454a123 |
container_end_page | |
container_issue | 1 |
container_start_page | 1257 |
container_title | Scientific reports |
container_volume | 15 |
creator | Plesinger, F. Hassouna, S. Carna, Z. Vesela, J. Smisek, R. Vargova, E. Sobota, V. Koscova, Z. Nejedly, P. Viscor, I. Prinzen, F. W. Jurak, P. Halamek, J. Osmancik, P. |
description | Electrical cardioversion presents one of the treatment options for atrial fibrillation (AF). However, the early recurrence rate is high, reaching ~40% three months after the procedure. Features based on vectorcardiographic signals were explored to find association with early recurrence of AF. Eighty-four patients with non-paroxysmal AF referred to electrical cardioversion were prospectively studied; early AF recurrence was present in 40 (47.6%). Patients underwent 24-h Holter ECG monitoring three months after the procedure to assess AF recurrence. Pre-procedural 12-lead ECGs (10 s, 1 kHz) were recorded and automatically analyzed. We explored associations of VCG-based features with early AF recurrence. Two features were strongly associated with AF recurrence: (1) a mean VCG (y-axis) signal slope in a window starting 145 ms before QRS center, lasting for 190 ms (AUC 0.778,
p
|
doi_str_mv | 10.1038/s41598-025-85340-4 |
format | article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_crossref_primary_10_1038_s41598_025_85340_4</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3152801781</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2274-414058dadb87211278da1085b779e994e7e7d7f3fa8b3bd5b51fd54b40454a123</originalsourceid><addsrcrecordid>eNp9kc1u1TAQhSMEolXpC7BAltiwCXj8g50Vqir-pEpsYG05zuReV7nxZexcVN6At8aXlFJY4I1Hms9n5vg0zVPgL4FL-yor0J1tudCt1VLxVj1oTgVXuhVSiIf36pPmPOdrXo8WnYLucXMiO2M604nT5sfFUtLOlxj8NN2wtC9xF7_jwA4YSqLgaYhpQ36_jYGN6MtCmJknZD7nFKIvlf0Wy5YRhoUI54AsjcwXin5iY-wpTlPVTzPzY0FiOFVlOs5jq_oBKdf2k-bR6KeM57f3WfPl3dvPlx_aq0_vP15eXLVBCKNaBYprO_iht0YACFNr4Fb31RF2nUKDZjCjHL3tZT_oXsM4aNWr-h3Kg5BnzZtVd7_0OxwCzoX85PYUd55uXPLR_d2Z49Zt0sEBGADZqarw4laB0tcFc3G7mANWmzOmJTsJWloLhr-u6PN_0Ou00Fz9HSlhORgLlRIrFSjlTDjebQPcHdN2a9qupu1-pe2OWzy77-Puye9sKyBXINfWvEH6M_s_sj8BZay5Zw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3152801781</pqid></control><display><type>article</type><title>Automatically optimized vectorcardiographic features are associated with recurrence of atrial fibrillation after electrical cardioversion</title><source>PubMed Central (Open Access)</source><source>Publicly Available Content Database</source><source>Free Full-Text Journals in Chemistry</source><source>Springer Nature - nature.com Journals - Fully Open Access</source><creator>Plesinger, F. ; Hassouna, S. ; Carna, Z. ; Vesela, J. ; Smisek, R. ; Vargova, E. ; Sobota, V. ; Koscova, Z. ; Nejedly, P. ; Viscor, I. ; Prinzen, F. W. ; Jurak, P. ; Halamek, J. ; Osmancik, P.</creator><creatorcontrib>Plesinger, F. ; Hassouna, S. ; Carna, Z. ; Vesela, J. ; Smisek, R. ; Vargova, E. ; Sobota, V. ; Koscova, Z. ; Nejedly, P. ; Viscor, I. ; Prinzen, F. W. ; Jurak, P. ; Halamek, J. ; Osmancik, P.</creatorcontrib><description>Electrical cardioversion presents one of the treatment options for atrial fibrillation (AF). However, the early recurrence rate is high, reaching ~40% three months after the procedure. Features based on vectorcardiographic signals were explored to find association with early recurrence of AF. Eighty-four patients with non-paroxysmal AF referred to electrical cardioversion were prospectively studied; early AF recurrence was present in 40 (47.6%). Patients underwent 24-h Holter ECG monitoring three months after the procedure to assess AF recurrence. Pre-procedural 12-lead ECGs (10 s, 1 kHz) were recorded and automatically analyzed. We explored associations of VCG-based features with early AF recurrence. Two features were strongly associated with AF recurrence: (1) a mean VCG (y-axis) signal slope in a window starting 145 ms before QRS center, lasting for 190 ms (AUC 0.778,
p
< 0.001), and (2) a mean VCG (z-axis) signal slope in a window starting 60 ms after QRS center, lasting for 465 ms (AUC 0.744,
p
< 0.001). These features showed higher association to the outcome than eighteen baseline clinical features. Our approach revealed features based on a slope of vectorcardiographic signals. This work also suggests that state of ventricles strongly affects the AF recurrence after electrical cardioversion.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/s41598-025-85340-4</identifier><identifier>PMID: 39779792</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>631/443/592/75/29/1309 ; 639/705/1041 ; 639/705/1042 ; Aged ; Atrial Fibrillation - physiopathology ; Atrial Fibrillation - therapy ; Cardiac arrhythmia ; Cardioversion ; EKG ; Electric Countershock ; Electrocardiography, Ambulatory ; Female ; Fibrillation ; Humanities and Social Sciences ; Humans ; Male ; Middle Aged ; multidisciplinary ; Patients ; Prospective Studies ; Recurrence ; Science ; Science (multidisciplinary) ; Treatment Outcome ; Vectorcardiography - methods</subject><ispartof>Scientific reports, 2025-01, Vol.15 (1), p.1257, Article 1257</ispartof><rights>The Author(s) 2025</rights><rights>2025. The Author(s).</rights><rights>Copyright Nature Publishing Group 2025</rights><rights>The Author(s) 2025 2025</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c2274-414058dadb87211278da1085b779e994e7e7d7f3fa8b3bd5b51fd54b40454a123</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/3152801781/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/3152801781?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25751,27922,27923,37010,37011,44588,53789,53791,74896</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39779792$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Plesinger, F.</creatorcontrib><creatorcontrib>Hassouna, S.</creatorcontrib><creatorcontrib>Carna, Z.</creatorcontrib><creatorcontrib>Vesela, J.</creatorcontrib><creatorcontrib>Smisek, R.</creatorcontrib><creatorcontrib>Vargova, E.</creatorcontrib><creatorcontrib>Sobota, V.</creatorcontrib><creatorcontrib>Koscova, Z.</creatorcontrib><creatorcontrib>Nejedly, P.</creatorcontrib><creatorcontrib>Viscor, I.</creatorcontrib><creatorcontrib>Prinzen, F. W.</creatorcontrib><creatorcontrib>Jurak, P.</creatorcontrib><creatorcontrib>Halamek, J.</creatorcontrib><creatorcontrib>Osmancik, P.</creatorcontrib><title>Automatically optimized vectorcardiographic features are associated with recurrence of atrial fibrillation after electrical cardioversion</title><title>Scientific reports</title><addtitle>Sci Rep</addtitle><addtitle>Sci Rep</addtitle><description>Electrical cardioversion presents one of the treatment options for atrial fibrillation (AF). However, the early recurrence rate is high, reaching ~40% three months after the procedure. Features based on vectorcardiographic signals were explored to find association with early recurrence of AF. Eighty-four patients with non-paroxysmal AF referred to electrical cardioversion were prospectively studied; early AF recurrence was present in 40 (47.6%). Patients underwent 24-h Holter ECG monitoring three months after the procedure to assess AF recurrence. Pre-procedural 12-lead ECGs (10 s, 1 kHz) were recorded and automatically analyzed. We explored associations of VCG-based features with early AF recurrence. Two features were strongly associated with AF recurrence: (1) a mean VCG (y-axis) signal slope in a window starting 145 ms before QRS center, lasting for 190 ms (AUC 0.778,
p
< 0.001), and (2) a mean VCG (z-axis) signal slope in a window starting 60 ms after QRS center, lasting for 465 ms (AUC 0.744,
p
< 0.001). These features showed higher association to the outcome than eighteen baseline clinical features. Our approach revealed features based on a slope of vectorcardiographic signals. This work also suggests that state of ventricles strongly affects the AF recurrence after electrical cardioversion.</description><subject>631/443/592/75/29/1309</subject><subject>639/705/1041</subject><subject>639/705/1042</subject><subject>Aged</subject><subject>Atrial Fibrillation - physiopathology</subject><subject>Atrial Fibrillation - therapy</subject><subject>Cardiac arrhythmia</subject><subject>Cardioversion</subject><subject>EKG</subject><subject>Electric Countershock</subject><subject>Electrocardiography, Ambulatory</subject><subject>Female</subject><subject>Fibrillation</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>multidisciplinary</subject><subject>Patients</subject><subject>Prospective Studies</subject><subject>Recurrence</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Treatment Outcome</subject><subject>Vectorcardiography - methods</subject><issn>2045-2322</issn><issn>2045-2322</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2025</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><recordid>eNp9kc1u1TAQhSMEolXpC7BAltiwCXj8g50Vqir-pEpsYG05zuReV7nxZexcVN6At8aXlFJY4I1Hms9n5vg0zVPgL4FL-yor0J1tudCt1VLxVj1oTgVXuhVSiIf36pPmPOdrXo8WnYLucXMiO2M604nT5sfFUtLOlxj8NN2wtC9xF7_jwA4YSqLgaYhpQ36_jYGN6MtCmJknZD7nFKIvlf0Wy5YRhoUI54AsjcwXin5iY-wpTlPVTzPzY0FiOFVlOs5jq_oBKdf2k-bR6KeM57f3WfPl3dvPlx_aq0_vP15eXLVBCKNaBYprO_iht0YACFNr4Fb31RF2nUKDZjCjHL3tZT_oXsM4aNWr-h3Kg5BnzZtVd7_0OxwCzoX85PYUd55uXPLR_d2Z49Zt0sEBGADZqarw4laB0tcFc3G7mANWmzOmJTsJWloLhr-u6PN_0Ou00Fz9HSlhORgLlRIrFSjlTDjebQPcHdN2a9qupu1-pe2OWzy77-Puye9sKyBXINfWvEH6M_s_sj8BZay5Zw</recordid><startdate>20250108</startdate><enddate>20250108</enddate><creator>Plesinger, F.</creator><creator>Hassouna, S.</creator><creator>Carna, Z.</creator><creator>Vesela, J.</creator><creator>Smisek, R.</creator><creator>Vargova, E.</creator><creator>Sobota, V.</creator><creator>Koscova, Z.</creator><creator>Nejedly, P.</creator><creator>Viscor, I.</creator><creator>Prinzen, F. W.</creator><creator>Jurak, P.</creator><creator>Halamek, J.</creator><creator>Osmancik, P.</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20250108</creationdate><title>Automatically optimized vectorcardiographic features are associated with recurrence of atrial fibrillation after electrical cardioversion</title><author>Plesinger, F. ; Hassouna, S. ; Carna, Z. ; Vesela, J. ; Smisek, R. ; Vargova, E. ; Sobota, V. ; Koscova, Z. ; Nejedly, P. ; Viscor, I. ; Prinzen, F. W. ; Jurak, P. ; Halamek, J. ; Osmancik, P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2274-414058dadb87211278da1085b779e994e7e7d7f3fa8b3bd5b51fd54b40454a123</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2025</creationdate><topic>631/443/592/75/29/1309</topic><topic>639/705/1041</topic><topic>639/705/1042</topic><topic>Aged</topic><topic>Atrial Fibrillation - physiopathology</topic><topic>Atrial Fibrillation - therapy</topic><topic>Cardiac arrhythmia</topic><topic>Cardioversion</topic><topic>EKG</topic><topic>Electric Countershock</topic><topic>Electrocardiography, Ambulatory</topic><topic>Female</topic><topic>Fibrillation</topic><topic>Humanities and Social Sciences</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>multidisciplinary</topic><topic>Patients</topic><topic>Prospective Studies</topic><topic>Recurrence</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Treatment Outcome</topic><topic>Vectorcardiography - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Plesinger, F.</creatorcontrib><creatorcontrib>Hassouna, S.</creatorcontrib><creatorcontrib>Carna, Z.</creatorcontrib><creatorcontrib>Vesela, J.</creatorcontrib><creatorcontrib>Smisek, R.</creatorcontrib><creatorcontrib>Vargova, E.</creatorcontrib><creatorcontrib>Sobota, V.</creatorcontrib><creatorcontrib>Koscova, Z.</creatorcontrib><creatorcontrib>Nejedly, P.</creatorcontrib><creatorcontrib>Viscor, I.</creatorcontrib><creatorcontrib>Prinzen, F. W.</creatorcontrib><creatorcontrib>Jurak, P.</creatorcontrib><creatorcontrib>Halamek, J.</creatorcontrib><creatorcontrib>Osmancik, P.</creatorcontrib><collection>SpringerOpen (Open Access)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection (ProQuest Medical & Health Databases)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Science Journals</collection><collection>Biological Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Scientific reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Plesinger, F.</au><au>Hassouna, S.</au><au>Carna, Z.</au><au>Vesela, J.</au><au>Smisek, R.</au><au>Vargova, E.</au><au>Sobota, V.</au><au>Koscova, Z.</au><au>Nejedly, P.</au><au>Viscor, I.</au><au>Prinzen, F. W.</au><au>Jurak, P.</au><au>Halamek, J.</au><au>Osmancik, P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Automatically optimized vectorcardiographic features are associated with recurrence of atrial fibrillation after electrical cardioversion</atitle><jtitle>Scientific reports</jtitle><stitle>Sci Rep</stitle><addtitle>Sci Rep</addtitle><date>2025-01-08</date><risdate>2025</risdate><volume>15</volume><issue>1</issue><spage>1257</spage><pages>1257-</pages><artnum>1257</artnum><issn>2045-2322</issn><eissn>2045-2322</eissn><abstract>Electrical cardioversion presents one of the treatment options for atrial fibrillation (AF). However, the early recurrence rate is high, reaching ~40% three months after the procedure. Features based on vectorcardiographic signals were explored to find association with early recurrence of AF. Eighty-four patients with non-paroxysmal AF referred to electrical cardioversion were prospectively studied; early AF recurrence was present in 40 (47.6%). Patients underwent 24-h Holter ECG monitoring three months after the procedure to assess AF recurrence. Pre-procedural 12-lead ECGs (10 s, 1 kHz) were recorded and automatically analyzed. We explored associations of VCG-based features with early AF recurrence. Two features were strongly associated with AF recurrence: (1) a mean VCG (y-axis) signal slope in a window starting 145 ms before QRS center, lasting for 190 ms (AUC 0.778,
p
< 0.001), and (2) a mean VCG (z-axis) signal slope in a window starting 60 ms after QRS center, lasting for 465 ms (AUC 0.744,
p
< 0.001). These features showed higher association to the outcome than eighteen baseline clinical features. Our approach revealed features based on a slope of vectorcardiographic signals. This work also suggests that state of ventricles strongly affects the AF recurrence after electrical cardioversion.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>39779792</pmid><doi>10.1038/s41598-025-85340-4</doi><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 2045-2322 |
ispartof | Scientific reports, 2025-01, Vol.15 (1), p.1257, Article 1257 |
issn | 2045-2322 2045-2322 |
language | eng |
recordid | cdi_crossref_primary_10_1038_s41598_025_85340_4 |
source | PubMed Central (Open Access); Publicly Available Content Database; Free Full-Text Journals in Chemistry; Springer Nature - nature.com Journals - Fully Open Access |
subjects | 631/443/592/75/29/1309 639/705/1041 639/705/1042 Aged Atrial Fibrillation - physiopathology Atrial Fibrillation - therapy Cardiac arrhythmia Cardioversion EKG Electric Countershock Electrocardiography, Ambulatory Female Fibrillation Humanities and Social Sciences Humans Male Middle Aged multidisciplinary Patients Prospective Studies Recurrence Science Science (multidisciplinary) Treatment Outcome Vectorcardiography - methods |
title | Automatically optimized vectorcardiographic features are associated with recurrence of atrial fibrillation after electrical cardioversion |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-14T12%3A06%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Automatically%20optimized%20vectorcardiographic%20features%20are%20associated%20with%20recurrence%20of%20atrial%20fibrillation%20after%20electrical%20cardioversion&rft.jtitle=Scientific%20reports&rft.au=Plesinger,%20F.&rft.date=2025-01-08&rft.volume=15&rft.issue=1&rft.spage=1257&rft.pages=1257-&rft.artnum=1257&rft.issn=2045-2322&rft.eissn=2045-2322&rft_id=info:doi/10.1038/s41598-025-85340-4&rft_dat=%3Cproquest_pubme%3E3152801781%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c2274-414058dadb87211278da1085b779e994e7e7d7f3fa8b3bd5b51fd54b40454a123%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=3152801781&rft_id=info:pmid/39779792&rfr_iscdi=true |