About supramolecular systems for dynamically probing cells

This article reviews the state of the art in the development of strategies for generating supramolecular systems for dynamic cell studies. Dynamic systems are crucial to further our understanding of cell biology and are consequently at the heart of many medical applications. Increasing interest has...

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Bibliographic Details
Published in:Chemical Society reviews 2014-07, Vol.43 (13), p.4449-4469
Main Authors: Brinkmann, Jenny, Cavatorta, Emanuela, Sankaran, Shrikrishnan, Schmidt, Bettina, van Weerd, Jasper, Jonkheijm, Pascal
Format: Article
Language:English
Subjects:
Biocompatibility
Biology
Cell Biology
Dynamic tests
Dynamical systems
Dynamics
Hydrogen Bonding
Molecular Probes
Nanostructures
Rendering
State of the art
Strategy
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Summary:This article reviews the state of the art in the development of strategies for generating supramolecular systems for dynamic cell studies. Dynamic systems are crucial to further our understanding of cell biology and are consequently at the heart of many medical applications. Increasing interest has therefore been focused recently on rendering systems bioactive and dynamic that can subsequently be employed to engage with cells. Different approaches using supramolecular chemistry are reviewed with particular emphasis on their application in cell studies. We conclude with an outlook on future challenges for dynamic cell research and applications. Rendering molecular systems bioactive and dynamic makes them powerful tools for probing cell function.
ISSN:0306-0012
1460-4744
DOI:10.1039/c4cs00034j