Hydration of nitriles to amides by a chitin-supported ruthenium catalyst

Chitin-supported ruthenium (Ru/chitin) promotes the hydration of nitriles to carboxamides under aqueous conditions. The nitrile hydration can be performed on a gram-scale and is compatible with the presence of various functional groups including olefins, aldehydes, carboxylic esters and nitro and be...

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Bibliographic Details
Published in:RSC advances 2015, Vol.5 (16), p.12152-12160
Main Authors: Matsuoka, Aki, Isogawa, Takahiro, Morioka, Yuna, Knappett, Benjamin R., Wheatley, Andrew E. H., Saito, Susumu, Naka, Hiroshi
Format: Article
Language:English
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Summary:Chitin-supported ruthenium (Ru/chitin) promotes the hydration of nitriles to carboxamides under aqueous conditions. The nitrile hydration can be performed on a gram-scale and is compatible with the presence of various functional groups including olefins, aldehydes, carboxylic esters and nitro and benzyloxycarbonyl groups. The Ru/chitin catalyst is easily prepared from commercially available chitin, ruthenium( iii ) chloride and sodium borohydride. Analysis of Ru/chitin by high-resolution transmission electron microscopy indicates the presence of ruthenium nanoparticles on the chitin support.
ISSN:2046-2069
2046-2069
DOI:10.1039/C4RA15682J