Triterpenes from the fruits of Rosa laevigata with acetylcholinesterase and Aβ-aggregation inhibitory activities

A lupane-type triterpene ( 1 ) featuring a rare 2-hemiacetal moiety in its A ring and aromatic ester derivatives ( 2–6 ) were isolated from the fruits of R. laevigata and evaluated to possess acetylcholinesterase and Aβ-aggregation inhibitory activities. Their structures were determined by multi-spe...

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Bibliographic Details
Published in:RSC advances 2016, Vol.6 (3), p.2431-2435
Main Authors: Gao, Pin-Yi, Wang, Meng, Liu, Xue-Gui, Gao, Yi-Xing, Li, Jia-Luo, Zhang, Zhen-Xue, Lin, Hou-Wen, Song, Shao-Jiang
Format: Article
Language:English
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Summary:A lupane-type triterpene ( 1 ) featuring a rare 2-hemiacetal moiety in its A ring and aromatic ester derivatives ( 2–6 ) were isolated from the fruits of R. laevigata and evaluated to possess acetylcholinesterase and Aβ-aggregation inhibitory activities. Their structures were determined by multi-spectroscopic methods, chemosynthesis and CD analysis.
ISSN:2046-2069
2046-2069
DOI:10.1039/C5RA21590K