I 2 -TBHP-catalyzed one-pot highly efficient synthesis of 4,3-fused 1,2,4-triazoles from N-tosylhydrazones and aromatic N-heterocycles via intermolecular formal 1,3-dipolar cycloaddition

I -TBHP-catalyzed azomethine imine generation and subsequent regioselective 1,3-dipolar cycloaddition (DC) with aromatic N-heterocycles was developed to afford various 4,3-fused 1,2,4-triazoles in excellent yields. The method is operationally simple and highly efficient with broad functional group t...

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Bibliographic Details
Published in:Organic & biomolecular chemistry 2016-12, Vol.14 (47), p.11061-11064
Main Authors: Inturi, Surendra Babu, Kalita, Biswajit, Ahamed, A Jafar
Format: Article
Language:English
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Summary:I -TBHP-catalyzed azomethine imine generation and subsequent regioselective 1,3-dipolar cycloaddition (DC) with aromatic N-heterocycles was developed to afford various 4,3-fused 1,2,4-triazoles in excellent yields. The method is operationally simple and highly efficient with broad functional group tolerance.
ISSN:1477-0520
1477-0539
DOI:10.1039/c6ob01926a