Self-assembled fluorodendrimers in the co-delivery of fluorinated drugs and therapeutic genes

Fluorinated drugs now make up about 25% of all pharmaceuticals. However, versatile carriers are currently lacking for the delivery of fluorinated drugs. Here, we developed a fluorodendrimer as a versatile and multifunctional carrier for fluorinated drugs. The fluorodendrimer enables the co-delivery...

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Bibliographic Details
Published in:Polymer chemistry 2016-01, Vol.7 (13), p.2319-2322
Main Authors: Wang, Hui, Hu, Jingjing, Cai, Xiaopan, Xiao, Jianru, Cheng, Yiyun
Format: Article
Language:English
Subjects:
Cancer
Carriers
Carriers, Drug
Drug delivery systems
Drugs
Fluorination
Genes
Polymer chemistry
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Summary:Fluorinated drugs now make up about 25% of all pharmaceuticals. However, versatile carriers are currently lacking for the delivery of fluorinated drugs. Here, we developed a fluorodendrimer as a versatile and multifunctional carrier for fluorinated drugs. The fluorodendrimer enables the co-delivery of fluorinated anticancer drugs and therapeutic genes for synergistic cancer therapy. A fluorodendrimer enables the co-delivery of fluorinated anticancer drugs and therapeutic genes for synergistic cancer therapy.
ISSN:1759-9954
1759-9962
DOI:10.1039/c6py00153j