Self-assembled fluorodendrimers in the co-delivery of fluorinated drugs and therapeutic genes

Fluorinated drugs now make up about 25% of all pharmaceuticals. However, versatile carriers are currently lacking for the delivery of fluorinated drugs. Here, we developed a fluorodendrimer as a versatile and multifunctional carrier for fluorinated drugs. The fluorodendrimer enables the co-delivery...

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Published in:Polymer chemistry 2016-01, Vol.7 (13), p.2319-2322
Main Authors: Wang, Hui, Hu, Jingjing, Cai, Xiaopan, Xiao, Jianru, Cheng, Yiyun
Format: Article
Language:English
Subjects:
Cancer
Carriers
Carriers, Drug
Drug delivery systems
Drugs
Fluorination
Genes
Polymer chemistry
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cited_by cdi_FETCH-LOGICAL-c286t-b9db01ef3c7fa88374b8b38f2c136aa7dcd92e7b8c3a71f7ab1a59f7d6e5f8193
cites cdi_FETCH-LOGICAL-c286t-b9db01ef3c7fa88374b8b38f2c136aa7dcd92e7b8c3a71f7ab1a59f7d6e5f8193
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creator Wang, Hui
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description Fluorinated drugs now make up about 25% of all pharmaceuticals. However, versatile carriers are currently lacking for the delivery of fluorinated drugs. Here, we developed a fluorodendrimer as a versatile and multifunctional carrier for fluorinated drugs. The fluorodendrimer enables the co-delivery of fluorinated anticancer drugs and therapeutic genes for synergistic cancer therapy. A fluorodendrimer enables the co-delivery of fluorinated anticancer drugs and therapeutic genes for synergistic cancer therapy.
doi_str_mv 10.1039/c6py00153j
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source Royal Society of Chemistry
subjects Cancer
Carriers
Carriers, Drug
Drug delivery systems
Drugs
Fluorination
Genes
Polymer chemistry
title Self-assembled fluorodendrimers in the co-delivery of fluorinated drugs and therapeutic genes
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