Interactive luminescent gold nanocluster embedded dsDNA and cisplatin as model nanoparticles for cancer theranostics

Plasmid DNA embedded with luminescent gold nanoclusters were reacted with cisplatin to form composite nanoparticles (composite NPs) for theranostic applications. The composite NPs delivered the cisplatin to cervical cancer HeLa cells in vitro , inducing apoptosis mediated cell death. The luminescent...

Full description

Saved in:
Bibliographic Details
Published in:RSC advances 2016, Vol.6 (114), p.113053-113057
Main Authors: Chatterjee, Bandhan, Sahoo, Amaresh Kumar, Ghosh, Siddhartha Sankar, Chattopadhyay, Arun
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Plasmid DNA embedded with luminescent gold nanoclusters were reacted with cisplatin to form composite nanoparticles (composite NPs) for theranostic applications. The composite NPs delivered the cisplatin to cervical cancer HeLa cells in vitro , inducing apoptosis mediated cell death. The luminescent gold nanoclusters were simultaneously used for cellular imaging.
ISSN:2046-2069
2046-2069
DOI:10.1039/C6RA24325H