Nanoscale hydrophilic colloids with high relaxivity and low cytotoxicity based on Gd( iii ) complexes with Keplerate polyanions

The work introduces for the first time Mo-132-type Keplerates (Kp) and Gd 3+ ions as a basis for the one-pot synthesis of aqueous colloids with high longitudinal relaxivity ( r 1 = 96.4 mM −1 s −1 at 20 MHz). The hydrophilic coating of small (3–5 nm) Gd x (Kp) y -based cores provides their colloid s...

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Bibliographic Details
Published in:New journal of chemistry 2017, Vol.41 (13), p.5271-5275
Main Authors: Elistratova, Julia, Akhmadeev, Bulat, Gubaidullin, Aidar, Korenev, Vladimir, Sokolov, Maxim, Nizameev, Irek, Stepanov, Alexey, Ismaev, Ildus, Kadirov, Marsil, Voloshina, Alexandra, Mustafina, Asiya
Format: Article
Language:English
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Summary:The work introduces for the first time Mo-132-type Keplerates (Kp) and Gd 3+ ions as a basis for the one-pot synthesis of aqueous colloids with high longitudinal relaxivity ( r 1 = 96.4 mM −1 s −1 at 20 MHz). The hydrophilic coating of small (3–5 nm) Gd x (Kp) y -based cores provides their colloid stabilization, protection from degradation and low cytotoxicity.
ISSN:1144-0546
1369-9261
DOI:10.1039/C7NJ01237C