A core-shell structured Ni-Co@Pt/C nanocomposite-modified sensor for the voltammetric determination of pseudoephedrine HCl

Herein, a core-shell structured Ni-Co@Pt/C nanocomposite was developed for the determination of pseudoephedrine HCl (PSE) in drug samples. Different Ni-Co@Pt/C nanomaterials were fabricated by varying the Ni : Co atomic ratio using ethylene glycol as the reducing agent via an assisted microwave irra...

Full description

Saved in:
Bibliographic Details
Published in:New journal of chemistry 2018, Vol.42 (4), p.2658-2668
Main Author: Abdel Hameed, R. M
Format: Article
Language:English
Subjects:
Cobalt
Core-shell structure
Current density
Electrochemical impedance spectroscopy
Electron microscopy
Ethylene glycol
Kinetics
Nanocomposites
Nanomaterials
Nickel
Oxidation
Reproducibility
Voltammetry
X-ray diffraction
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Herein, a core-shell structured Ni-Co@Pt/C nanocomposite was developed for the determination of pseudoephedrine HCl (PSE) in drug samples. Different Ni-Co@Pt/C nanomaterials were fabricated by varying the Ni : Co atomic ratio using ethylene glycol as the reducing agent via an assisted microwave irradiation process. X-ray diffraction (XRD) and transmission electron microscopy (TEM) were conducted to characterize the prepared nanocomposite. Electrocatalytic activity of the Ni-Co@Pt/C nanocomposite for the determination of PSE was demonstrated using cyclic voltammetry, linear sweep voltammetry, differential pulse voltammetry, and electrochemical impedance spectroscopy. The PSE oxidation current density value was efficiently affected by the cobalt content in the fabricated Ni-Co@Pt/C nanocomposite. The maximum activity was achieved with the nanomaterial containing a Ni : Co atomic ratio of 1 : 3. Differential pulse voltammetry indicated a linear dependence of the oxidation current density on the PSE concentration up to 1400 μM. High sensitivity and good reproducibility and stability were displayed by the Ni-Co@Pt/C nanocomposite during the estimation of PSE. This would encourage the wide application of the proposed nanocomposite in the clinical assay of the studied drugs. Herein, a core-shell structured Ni-Co@Pt/C nanocomposite was developed for the determination of pseudoephedrine HCl (PSE) in drug samples.
ISSN:1144-0546
1369-9261
DOI:10.1039/c7nj04973k