Stereoselective aldol reactions using pseudo C 2 symmetric 1-benzyl-4-(trifluoromethyl)piperidine-2,6-dione

Crossed aldol reactions of the CF -containing pseudo C symmetric cyclic imide 3 were carried out by way of the corresponding boron bisenolate to stereoselectively furnish the desired products 4 and this procedure allowed the preferential construction of the diastereomers of the compounds previously...

Full description

Saved in:
Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2018-09, Vol.54 (71), p.9913-9916
Main Authors: Inoue, Yuta, Hatayama, Takahiro, Kawasaki-Takasuka, Tomoko, Agou, Tomohiro, Kubota, Toshio, Yamazaki, Takashi
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Crossed aldol reactions of the CF -containing pseudo C symmetric cyclic imide 3 were carried out by way of the corresponding boron bisenolate to stereoselectively furnish the desired products 4 and this procedure allowed the preferential construction of the diastereomers of the compounds previously obtained from the acyclic counterpart 1.
ISSN:1359-7345
1364-548X
DOI:10.1039/c8cc05458d