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A supramolecular hybrid material constructed from graphene oxide and a pillar[6]arene-based host-guest complex as an ultrasound and photoacoustic signal nanoamplifier

Photoacoustic imaging combines the merits of ultrasound imaging and optical imaging, and allows a fascinating imaging paradigm with deeper tissue penetration than optical imaging and higher spatial resolution than ultrasound imaging. Herein, we develop a supramolecular hybrid material composed of gr...

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Published in:Materials horizons 2018-01, Vol.5 (3), p.429-435
Main Authors: Yu, Guocan, Yang, Jie, Fu, Xiao, Wang, Zhantong, Shao, Li, Mao, Zhengwei, Liu, Yijing, Yang, Zhen, Zhang, Fuwu, Fan, Wenpei, Song, Jibin, Zhou, Zijian, Gao, Changyou, Huang, Feihe, Chen, Xiaoyuan
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Language:English
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Summary:Photoacoustic imaging combines the merits of ultrasound imaging and optical imaging, and allows a fascinating imaging paradigm with deeper tissue penetration than optical imaging and higher spatial resolution than ultrasound imaging. Herein, we develop a supramolecular hybrid material composed of graphene oxide (GO) and a pillar[6]arene-based host-guest complex ( CP6⊃PyN ), which can be used as an ultrasound (US) and photoacoustic (PA) signal nanoamplifier. Triggered by the near-infrared (NIR) light mediated photothermal effect, CO 2 nanobubbles are generated on the surface of GO@ CP6⊃PyN due to the decomposition of the bicarbonate counterions, thus strongly amplifying its US and PA performances. Our study, for the first time, demonstrates enhanced US and PA activity in a supramolecular hybrid material on the basis of host-guest chemistry as a photoacoustic nanoplatform. A supramolecular hybrid material is developed as ultrasound and photoacoustic signals nanoamplifier.
ISSN:2051-6347
2051-6355
DOI:10.1039/c8mh00128f