Chemoselective reduction of aldehydes via a combination of NaBH 4 and acetylacetone

A bench-stable combination of NaBH 4 -acetylacetone was developed for the efficient chemoselective reduction of aldehydes in the presence of ketones. This method offers a useful synthetic protocol for distinguishing carbonyl reaction sites, and its synthetic utility is reflected by its moisture tole...

Full description

Saved in:
Bibliographic Details
Published in:New journal of chemistry 2019-10, Vol.43 (39), p.15793-15796
Main Authors: Sui, Guoqing, Lv, Qingyun, Song, Xiaoqing, Guo, Huihui, Dai, Jiatong, Ren, Li, Lee, Chi-Sing, Zhou, Wenming, Hao, Hong-Dong
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A bench-stable combination of NaBH 4 -acetylacetone was developed for the efficient chemoselective reduction of aldehydes in the presence of ketones. This method offers a useful synthetic protocol for distinguishing carbonyl reaction sites, and its synthetic utility is reflected by its moisture tolerance and high efficiency in a variety of complex settings.
ISSN:1144-0546
1369-9261
DOI:10.1039/C9NJ03210J