A new amplification strategy for a quartz crystal microbalance miRNA sensor based on selective interactions between a metal-organic framework and miRNA

A new strategy of using a MOF as an effective amplifier in a QCM miRNA sensor was presented based on the selective interaction between a MOF (UiO-66) with different zeta potentials and different miRNAs. The signal can be significantly enhanced, which leads to significantly improved performance in mi...

Full description

Saved in:
Bibliographic Details
Published in:New journal of chemistry 2020-02, Vol.44 (5), p.1684-1688
Main Authors: Ma, Ding, Zheng, Sheng-Run, Fan, Jun, Cai, Song-Liang, Dai, Zong, Zou, Xiao-Yong, Teng, Shao-Hua, Zhang, Wei-Guang
Format: Article
Language:English
Subjects:
Metal-organic frameworks
Microbalances
Quartz crystals
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A new strategy of using a MOF as an effective amplifier in a QCM miRNA sensor was presented based on the selective interaction between a MOF (UiO-66) with different zeta potentials and different miRNAs. The signal can be significantly enhanced, which leads to significantly improved performance in miRNA detection. UiO-66 is used as an effective amplifier in a QCM miRNA sensor to detect Let-7a.
ISSN:1144-0546
1369-9261
DOI:10.1039/c9nj04600c