A new amplification strategy for a quartz crystal microbalance miRNA sensor based on selective interactions between a metal-organic framework and miRNA

A new strategy of using a MOF as an effective amplifier in a QCM miRNA sensor was presented based on the selective interaction between a MOF (UiO-66) with different zeta potentials and different miRNAs. The signal can be significantly enhanced, which leads to significantly improved performance in mi...

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Published in:New journal of chemistry 2020-02, Vol.44 (5), p.1684-1688
Main Authors: Ma, Ding, Zheng, Sheng-Run, Fan, Jun, Cai, Song-Liang, Dai, Zong, Zou, Xiao-Yong, Teng, Shao-Hua, Zhang, Wei-Guang
Format: Article
Language:English
Subjects:
Metal-organic frameworks
Microbalances
Quartz crystals
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cited_by cdi_FETCH-LOGICAL-c281t-3c1c342ab60435355e63f43c7879f28a61b0fb47d37034abcde01f27e2f4448a3
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container_issue 5
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container_title New journal of chemistry
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creator Ma, Ding
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description A new strategy of using a MOF as an effective amplifier in a QCM miRNA sensor was presented based on the selective interaction between a MOF (UiO-66) with different zeta potentials and different miRNAs. The signal can be significantly enhanced, which leads to significantly improved performance in miRNA detection. UiO-66 is used as an effective amplifier in a QCM miRNA sensor to detect Let-7a.
doi_str_mv 10.1039/c9nj04600c
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source Royal Society of Chemistry:Jisc Collections:Royal Society of Chemistry Read and Publish 2022-2024 (reading list)
subjects Metal-organic frameworks
Microbalances
Quartz crystals
title A new amplification strategy for a quartz crystal microbalance miRNA sensor based on selective interactions between a metal-organic framework and miRNA
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