Self-assembled CeVO 4 /Ag nanohybrid as photoconversion agents with enhanced solar-driven photocatalysis and NIR-responsive photothermal/photodynamic synergistic therapy performance

The plasmonic cerium vanadate (CeVO ) semiconductor and plasmonic silver (Ag) metal exhibit a localized surface plasmon resonance (LSPR) effect in the visible (Vis)-light region; however, weak absorption in the near-infrared (NIR) region restricts their environmental remediation and biomedical appli...

Full description

Saved in:
Bibliographic Details
Published in:Nanoscale 2019-05, Vol.11 (20), p.10129-10136
Main Authors: Chang, Mengyu, Wang, Meifang, Chen, Yeqing, Shu, Mengmeng, Zhao, Yajie, Ding, Binbin, Hou, Zhiyao, Lin, Jun
Format: Article
Language:English
Subjects:
Animals
Benzenesulfonates - chemistry
Benzenesulfonates - metabolism
Catalysis
Cell Line
Cell Survival - drug effects
Cerium - chemistry
HeLa Cells
Humans
Infrared Rays
Mice
Nanocomposites - chemistry
Nanocomposites - therapeutic use
Nanocomposites - toxicity
Neoplasms - diagnostic imaging
Neoplasms - drug therapy
Neoplasms - therapy
Oleic Acids - chemistry
Photochemotherapy
Phototherapy
Silver - chemistry
Transplantation, Heterologous
Vanadates - chemistry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The plasmonic cerium vanadate (CeVO ) semiconductor and plasmonic silver (Ag) metal exhibit a localized surface plasmon resonance (LSPR) effect in the visible (Vis)-light region; however, weak absorption in the near-infrared (NIR) region restricts their environmental remediation and biomedical application. Herein, CeVO /Ag nanohybrids with self-assembled heterostructure and improved Vis/NIR light absorption were synthesized from CeVO nanosheets and AgNO solution, which could serve as potential solar-driven catalytic agents and near-infrared (NIR) light responsive anticancer agents. Oleic acid-stabilized CeVO nanosheets were modified with the HS-PEG -OH by the thiol-ene click reaction and presented self-assembly morphology in aqueous solution due to hydrophobic-hydrophobic interactions. Sulfhydryl (-SH) groups provided stable sites for Ag ions on the surface of CeVO , and Ag ions could be directly reduced by Ce ions to form CeVO /Ag heterojunction nanocrystals (NCs). Due to the higher absorption in the Vis/NIR light region than CeVO nanosheets, CeVO /Ag NCs led to the improved solar light responsive photocatalytic degradation of organic dyes. Upon the exposure of these NCs to an 808 nm laser, CeVO /Ag NCs show high photothermal conversion efficiency, ROS generation ability and photoacoustic (PA) signal for implementing PA imaging-guided photothermal/photodynamic synergistic cancer therapy with better tumor inhibition effect.
ISSN:2040-3364
2040-3372
DOI:10.1039/c9nr02412c