Construction of a novel "ball-and-rod" MSNs-pp-PEG system: a promising antitumor drug delivery system with a particle size switchable function

To utilize the advantages of drug carriers of different sizes, a size switchable "ball-and-rod" drug delivery system was constructed, which could switch its size in response to enzymes in tumors. It would be a promising system with long circulation and deep penetration properties, which en...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2020-04, Vol.56 (35), p.4785-4788
Main Authors: He, Xin, Wang, Dong, Chen, Peng, Qiao, Youbei, Yang, Tiehong, Yu, Zhe, Wang, Chaoli, Wu, Hong
Format: Article
Language:English
Subjects:
Drug carriers
Drug delivery systems
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Summary:To utilize the advantages of drug carriers of different sizes, a size switchable "ball-and-rod" drug delivery system was constructed, which could switch its size in response to enzymes in tumors. It would be a promising system with long circulation and deep penetration properties, which enable its application in tumor treatment. The "ball-and-rod" drug delivery system achieved a size-switchable goal in tumors due to its properties of long circulation and deep penetration.
ISSN:1359-7345
1364-548X
DOI:10.1039/d0cc00600a