Investigating the growth of hyperbranched polymers by self-condensing vinyl RAFT copolymerization from the surface of upconversion nanoparticles

Hyperbranched poly( N -(2-hydroxypropyl) methacrylamide)s grafted on upconversion nanoparticles (UCNPs) were prepared by surface-initiated self-condensing vinyl RAFT copolymerization from the surface of UCNPs modified with a RAFT chain transfer agent. The effect of the grafting density in RAFT chain...

Full description

Saved in:
Bibliographic Details
Published in:Polymer chemistry 2020-07, Vol.11 (26), p.4313-4325
Main Authors: Kavand, Alireza, Blanck, Christian, Przybilla, Frédéric, Mély, Yves, Anton, Nicolas, Vandamme, Thierry, Serra, Christophe A, Chan-Seng, Delphine
Format: Article
Language:English
Subjects:
Addition polymerization
Chain transfer
Chemical Sciences
Copolymerization
Medical imaging
Methacrylamide
Nanoparticles
Polymer chemistry
Polymerization
Polymers
Propagation (polymerization)
Termination (polymerization)
Upconversion
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Hyperbranched poly( N -(2-hydroxypropyl) methacrylamide)s grafted on upconversion nanoparticles (UCNPs) were prepared by surface-initiated self-condensing vinyl RAFT copolymerization from the surface of UCNPs modified with a RAFT chain transfer agent. The effect of the grafting density in RAFT chain transfer agent on UCNPs and the concentration in transmer were investigated. The propagation of the polymerization was strongly affected by termination and transfer reactions associated with the high local concentration in propagating chains due to the immobilization of the polymer chains at the surface of UCNPs and increased number of active centers during the polymerization, but also to the hopping and rolling mechanisms related to the surface-initiated RAFT polymerization. The development of such nanohybrids opens the way to novel nano-objects for biomedical imaging and theranostics. The growth of hyperbranched polymers by self-condensing vinyl polymerization under RAFT conditions from the surface of upconversion nanoparticles is hindered by steric hinderance, but also increased termination and transfer reactions.
ISSN:1759-9954
1759-9962
DOI:10.1039/d0py00452a