Effects of ruthenium hydride species on primary amine synthesis by direct amination of alcohols over a heterogeneous Ru catalyst

Heterogeneously catalysed synthesis of primary amines by direct amination of alcohols with ammonia has long been an elusive goal. In contrast to reported Ru-based catalytic systems, we report that Ru-MgO/TiO 2 acts as an effective heterogeneous catalyst for the direct amination of a variety of alcoh...

Full description

Saved in:
Bibliographic Details
Published in:Chemical science (Cambridge) 2020-09, Vol.11 (36), p.9884-989
Main Authors: Kita, Yusuke, Kuwabara, Midori, Yamadera, Satoshi, Kamata, Keigo, Hara, Michikazu
Format: Article
Language:English
Subjects:
Alcohol
Alcohols
Amines
Ammonia
Catalysts
Chemical synthesis
Chemistry
Hydrides
Low temperature
Magnesium oxide
Ruthenium
System effectiveness
Titanium dioxide
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Heterogeneously catalysed synthesis of primary amines by direct amination of alcohols with ammonia has long been an elusive goal. In contrast to reported Ru-based catalytic systems, we report that Ru-MgO/TiO 2 acts as an effective heterogeneous catalyst for the direct amination of a variety of alcohols to primary amines at low temperatures of ca. 100 °C without the introduction of H 2 gas. The present system could be applied to a variety of alcohols and provides an efficient synthetic route for 2,5-bis(aminomethyl)furan (BAMF), an attention-getting biomonomer. The high catalytic performance can be rationalized by the reactivity tuning of Ru-H species using MgO. Spectroscopic measurements suggest that MgO enhances the reactivity of hydride species by electron donation from MgO to Ru. Ru-MgO/TiO 2 exhibited high catalytic performance for direct amination of alcohols based on the acceleration effects of MgO.
ISSN:2041-6520
2041-6539
DOI:10.1039/d0sc03858j