Water-soluble AIE-active fluorescent organic nanoparticles for ratiometric detection of SO 2 in the mitochondria of living cells

We report a water-soluble AIEgen (TYDL) to be self-assembled into fluorescent organic nanoparticles (TYDLs) for specific sensing of SO in living hepatoma cells. It is demonstrated that the TYDLs were suitable for ratiometrically detecting endogenous and exogenous SO in mitochondria with good selecti...

Full description

Saved in:
Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2022-06, Vol.58 (46), p.6618-6621
Main Authors: Feng, Gai-Li, Liu, Yi-Chen, Ji, Yan-Ming, Zhou, Wei, Li, Xia-Fen, Hou, Min, Gao, Jie-Lei, Zhang, Yuan, Xing, Guo-Wen
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We report a water-soluble AIEgen (TYDL) to be self-assembled into fluorescent organic nanoparticles (TYDLs) for specific sensing of SO in living hepatoma cells. It is demonstrated that the TYDLs were suitable for ratiometrically detecting endogenous and exogenous SO in mitochondria with good selectivity, low detection limit (75 nM) and excellent photostability (>30 min). These findings imply the great potential applications of TYDLs for the diagnosis of SO -related diseases in cell biology.
ISSN:1359-7345
1364-548X
DOI:10.1039/D2CC02168D