Dual-channel lanthanide-doped nanoprobe for reliable multi-signal ratiometric detection of H 2 S in whole blood

Wavelength-dependent absorbance of blood has impeded the development of fluorescence biodetection in whole blood. Here, by replacing the fluorescence working signal with a temperature signal, reliable H 2 S detection was performed in samples of whole blood. The developed system was based on a dual-c...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2022-08, Vol.58 (69), p.9642-9645
Main Authors: Wei, Zheng, Cao, Tianqi, Li, Luoyuan, Zhu, Xingjun, Zhou, Jing, Liu, Yuxin
Format: Article
Language:English
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Summary:Wavelength-dependent absorbance of blood has impeded the development of fluorescence biodetection in whole blood. Here, by replacing the fluorescence working signal with a temperature signal, reliable H 2 S detection was performed in samples of whole blood. The developed system was based on a dual-channel lanthanide-doped nanoprobe, which further allowed precise serodiagnosis of acute pancreatitis.
ISSN:1359-7345
1364-548X
DOI:10.1039/D2CC03360G