Dual-channel lanthanide-doped nanoprobe for reliable multi-signal ratiometric detection of H 2 S in whole blood

Wavelength-dependent absorbance of blood has impeded the development of fluorescence biodetection in whole blood. Here, by replacing the fluorescence working signal with a temperature signal, reliable H 2 S detection was performed in samples of whole blood. The developed system was based on a dual-c...

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Published in:Chemical communications (Cambridge, England) England), 2022-08, Vol.58 (69), p.9642-9645
Main Authors: Wei, Zheng, Cao, Tianqi, Li, Luoyuan, Zhu, Xingjun, Zhou, Jing, Liu, Yuxin
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Language:English
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creator Wei, Zheng
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Zhou, Jing
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description Wavelength-dependent absorbance of blood has impeded the development of fluorescence biodetection in whole blood. Here, by replacing the fluorescence working signal with a temperature signal, reliable H 2 S detection was performed in samples of whole blood. The developed system was based on a dual-channel lanthanide-doped nanoprobe, which further allowed precise serodiagnosis of acute pancreatitis.
doi_str_mv 10.1039/D2CC03360G
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title Dual-channel lanthanide-doped nanoprobe for reliable multi-signal ratiometric detection of H 2 S in whole blood
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