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Photoredox-catalyzed fluorodifluoroacetylation of alkenes with FSO 2 CF 2 CO 2 Me and Et 3 N·3HF

Photoredox-catalyzed three-component fluorodifluoroacetylation of aromatic alkenes is reported, which features a wide substrate scope and functional group tolerance. An advantage of the reaction is the use of a nucleophilic fluoride source and a general difluoroacetylation reagent for the fluorodifl...

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Bibliographic Details
Published in:Organic & biomolecular chemistry 2022-05, Vol.20 (18), p.3726-3730
Main Authors: Zou, Song, Luo, Xuewei, Chen, Chao, Xi, Chanjuan
Format: Article
Language:English
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Summary:Photoredox-catalyzed three-component fluorodifluoroacetylation of aromatic alkenes is reported, which features a wide substrate scope and functional group tolerance. An advantage of the reaction is the use of a nucleophilic fluoride source and a general difluoroacetylation reagent for the fluorodifluoroacetylation of alkenes.
ISSN:1477-0520
1477-0539
DOI:10.1039/D2OB00488G