Highly stable, protein resistant thin films on SiC-modified silicon substrates

Thin films terminated with oligo(ethylene glycol) (OEG) could be photochemically grafted onto ultrathin silicon carbide layers that were generated on silicon substrates via carbonization with acetylene at 820 °C. The OEG coating reduced the non-specific adsorption of fibrinogen on the substrates by...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2010-01, Vol.46 (19), p.3289-3291
Main Authors: Qin, Guoting, Zhang, Rui, Makarenko, Boris, Kumar, Amit, Rabalais, Wayne, López Romero, J. Manuel, Rico, Rodrigo, Cai, Chengzhi
Format: Article
Language:English
Subjects:
Adsorption
Carbon Compounds, Inorganic - chemistry
Fibrinogen - chemistry
Membranes, Artificial
Photochemistry
Polyethylene Glycols - chemistry
Silicon - chemistry
Silicon Compounds - chemistry
Surface Properties
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Summary:Thin films terminated with oligo(ethylene glycol) (OEG) could be photochemically grafted onto ultrathin silicon carbide layers that were generated on silicon substrates via carbonization with acetylene at 820 °C. The OEG coating reduced the non-specific adsorption of fibrinogen on the substrates by 99.5% and remained resistant after storage in PBS for 4 weeks at 37 °C. Thin films terminated with oligo(ethylene glycol) could be photochemically grafted onto ultrathin SiC layers that were grown on silicon substrates via carbonization. They reduced the non-specific adsorption of fibrinogen on the substrates by 99.5% and remained so after storage in PBS buffer for 4 weeks at 37 °C.
ISSN:1359-7345
1364-548X
DOI:10.1039/b925708j