Aptamer-based suspension array indexed by structural color and shape

A suspension array with microcarriers encoded by both structural color and shape was developed. The microcarriers with high stability, large capacity, low background noise and simplicity for practical application were the hydrogel colloidal crystals fabricated by photolithography. The aptamer based...

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Bibliographic Details
Published in:Journal of materials chemistry 2011-01, Vol.21 (46), p.18659-18664
Main Authors: Ye, Bao-Fen, Zhao, Yuan-Jin, Li, Ting-Ting, Xie, Zhuo-Ying, Gu, Zhong-Ze
Format: Article
Language:English
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Summary:A suspension array with microcarriers encoded by both structural color and shape was developed. The microcarriers with high stability, large capacity, low background noise and simplicity for practical application were the hydrogel colloidal crystals fabricated by photolithography. The aptamer based multiplex array, as an example, was constructed using the encoded microcarriers as the carrier of suspension array. The ssDNA functionalized hydrogel microcarriers are achieved by co-polymerization. Based on the high selectivity recognition of aptamer to its target, a novel hydrogel microcarrier suspension array platform, as a potential tool for the efficient quantification of biomolecules, is established. A suspension array with photonic crystal microcarriers encoded by both structural color and shape was developed. A proof-of-concept aptamer based multiplex study was demonstrated.
ISSN:0959-9428
1364-5501
DOI:10.1039/c1jm14009d