Restoration of Vision by Radiotherapy for Severe, Acute, Steroid-Refractory, Congestive Thyroid Orbitopathy

We report the case history of a patient treated with radiotherapy for severe acute thyroid orbitopathy that failed to respond to high-dose corticosteroid therapy. The clinical response to irradiation was rapid, dramatic and sustained after extended follow-up. Although radiotherapy has been used in d...

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Bibliographic Details
Published in:Clinical oncology (Royal College of Radiologists (Great Britain)) 2000-06, Vol.12 (3), p.188-191
Main Authors: MacAndie, K., Harnett, A.N., Kyle, P.
Format: Article
Language:English
Subjects:
Graves' ophthalmopathy
Radiotherapy
Thyroid orbitopathy
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Summary:We report the case history of a patient treated with radiotherapy for severe acute thyroid orbitopathy that failed to respond to high-dose corticosteroid therapy. The clinical response to irradiation was rapid, dramatic and sustained after extended follow-up. Although radiotherapy has been used in dysthyroid eye disease, there remains debate over the precise indications for and the timing of its utilization. A review of the literature on the use of radiotherapy for acute thyroid orbitopathy has been undertaken, emphasizing its steroid-sparing potential and its role in avoiding the necessity for surgical orbital decompression.
ISSN:0936-6555
1433-2981
DOI:10.1053/clon.2000.9148