Renal Dysfunction and Arrhythmia Association in Patients Receiving Milrinone After Cardiac Surgery

[Display omitted] The altered pharmacokinetics of milrinone in renal impairment could result in an increased risk of cardiac arrhythmias. This study aimed to determine if there is an association between new-onset arrhythmias and renal impairment after cardiac surgery following milrinone administrati...

Full description

Saved in:
Bibliographic Details
Published in:Journal of cardiothoracic and vascular anesthesia 2023-03, Vol.37 (3), p.353-359
Main Authors: Valkovec, Amy M., Kram, Shawn J., Henderson, James B., Levy, Jerrold H.
Format: Article
Language:English
Subjects:
Adult
Arrhythmias, Cardiac - drug therapy
Arrhythmias, Cardiac - etiology
cardiac inotropism
Cardiotonic Agents
Coronary Artery Bypass
Humans
inotropic agents, positive cardiac
Kidney Diseases - drug therapy
Milrinone
renal insufficiency
Retrospective Studies
thoracic surgery
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:[Display omitted] The altered pharmacokinetics of milrinone in renal impairment could result in an increased risk of cardiac arrhythmias. This study aimed to determine if there is an association between new-onset arrhythmias and renal impairment after cardiac surgery following milrinone administration. A retrospective cohort study. A single-center tertiary care hospital. Adult patients who received a milrinone infusion in the intensive care unit (ICU) setting after coronary artery bypass graft, valvuloplasty, annuloplasty, or a combination of these surgeries from July 1, 2014 to July 1, 2021. Renal impairment was defined using a creatinine clearance
ISSN:1053-0770
1532-8422
DOI:10.1053/j.jvca.2022.11.027