Musculoskeletal disorders: an introduction

Musculoskeletal disorders remain the most common cause of physical disability in an ageing population. The importance of increased cardiovascular disease in this group is being recognized. The dramatic therapeutic impact of the cytokine specific inhibitors in the treatment of inflammatory joint dise...

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Bibliographic Details
Published in:Medicine (Abingdon. 1995, UK ed.) UK ed.), 2006-09, Vol.34 (9), p.331-332
Main Author: Griffiths, Ian D.
Format: Article
Language:English
Subjects:
anti CCP
anti cytokines
cardiovascular disease
Cox-2 inhibitors
disability
ultrasound
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Summary:Musculoskeletal disorders remain the most common cause of physical disability in an ageing population. The importance of increased cardiovascular disease in this group is being recognized. The dramatic therapeutic impact of the cytokine specific inhibitors in the treatment of inflammatory joint disease has been balanced by the controversy over the potential cardiovascular toxicity of the newer selective Cox-2 inhibitors. Ultrasound is rapidly emerging as a valuable diagnostic tool and circulating anti-cyclical citrullinated peptide (anti-CCP) antibodies seem a promising early diagnostic and prognostic test in rheumatoid arthritis.
ISSN:1357-3039
1878-9390
DOI:10.1053/j.mpmed.2006.06.006