Cell and Biomimetic Scaffold Based Approaches for Cartilage Regeneration

This chapter discusses tissue engineering approaches in the repair of focal cartilage defects and degenerative joint conditions. It introduces the traditionally applied methods and provides a look at newer clinical and pre-clinical cell-based therapies for these treatments. In addition, cutting-edge...

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Bibliographic Details
Published in:Operative techniques in orthopaedics 2016-09, Vol.26 (3), p.135-146
Main Authors: Sun, Aaron X, Numpaisal, Piya-on, MD, Gottardi, Riccardo, PhD, Shen, He, PhD, Yang, Guang, PhD, Tuan, Rocky S, PhD
Format: Article
Language:English
Subjects:
Orthopedics
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Summary:This chapter discusses tissue engineering approaches in the repair of focal cartilage defects and degenerative joint conditions. It introduces the traditionally applied methods and provides a look at newer clinical and pre-clinical cell-based therapies for these treatments. In addition, cutting-edge approaches, both on the cellular front and the scaffold fabrication front, are examined for potential clinical application. Finally, the chapter closes with a look at future perspectives and directions in studying and understanding degenerative joint diseases.
ISSN:1048-6666
1558-3848
DOI:10.1053/j.oto.2016.06.003