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Synthesis of Fluorinated Thiophenes and Their Analogues

Abstract Approaches towards fluorothiophenes, perfluoroalkyl­thiophenes, perfluoroarylthiophenes and their benzo-analogues are reviewed. The literature up to 2010 is highlighted. 1 Introduction 2 Synthesis of Fluorothiophenes 2.1 Functionalization of the Thiophene Ring 2.2 Heterocyclization 3 Synthe...

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Published in:Synthesis (Stuttgart) 2011-08, Vol.2011 (16), p.2505-2529
Main Authors: Serdyuk, Olga V., Abaev, Vladimir T., Butin, Alexander V., Nenajdenko, Valentine G.
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Language:English
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creator Serdyuk, Olga V.
Abaev, Vladimir T.
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description Abstract Approaches towards fluorothiophenes, perfluoroalkyl­thiophenes, perfluoroarylthiophenes and their benzo-analogues are reviewed. The literature up to 2010 is highlighted. 1 Introduction 2 Synthesis of Fluorothiophenes 2.1 Functionalization of the Thiophene Ring 2.2 Heterocyclization 3 Synthesis of Perfluoroalkylthiophenes 3.1 Functionalization of the Thiophene Ring 3.2 Heterocyclization and Cycloaddition 4 Synthesis of Fluorobenzothiophenes 5 Synthesis of Perfluoroalkylbenzothiophenes 6 Synthesis of Perfluoroarylthiophenes 6.1 Organometallic Synthesis 6.2 Cross-Coupling 6.3 Heterocyclization 7 Synthesis of Perfluoroarylbenzothiophenes 8 Synthesis of Benzothiophenes with a Perfluorinated Carbocycle 9 Conclusions
doi_str_mv 10.1055/s-0030-1260088
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title Synthesis of Fluorinated Thiophenes and Their Analogues
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