Fast Assembly of 1H-Imidazo[1,2-a]imidazol-5-amines via Groebke–Blackburn–Bienaymé Reaction with 2-Aminoimidazoles

Abstract A novel microwave-assisted protocol allowing the ­successful application of 2-aminoimidazoles in the Groebke–­Blackburn–Bienaymé reaction for the facile construction of the 1 H -imidazo[1,2- a ]imidazol-5-amine core was developed.

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Bibliographic Details
Published in:Synlett 2013-02, Vol.24 (3), p.351-354
Main Authors: Pereshivko, Olga P., Peshkov, Vsevolod A., Ermolat’ev, Denis S., Van der Eycken, Erik V.
Format: Article
Language:English
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Summary:Abstract A novel microwave-assisted protocol allowing the ­successful application of 2-aminoimidazoles in the Groebke–­Blackburn–Bienaymé reaction for the facile construction of the 1 H -imidazo[1,2- a ]imidazol-5-amine core was developed.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-0032-1317986