One-Pot Synthesis of 3-Methylflavones and Their Transformation into (E)-3-Styrylflavones via Wittig Reactions

Abstract An efficient one-pot synthesis of 3-methylflavone derivatives is established. Furthermore, their transformation into phosphorus ylides, which are then used in the diastereoselective synthesis of ( E )-styrylflavones through Wittig reactions, is also studied.

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Bibliographic Details
Published in:Synlett 2013-12, Vol.24 (20), p.2683-2686
Main Authors: Rocha, Djenisa H. A., Pinto, Diana C. G. A., Silva, Artur M. S.
Format: Article
Language:English
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Summary:Abstract An efficient one-pot synthesis of 3-methylflavone derivatives is established. Furthermore, their transformation into phosphorus ylides, which are then used in the diastereoselective synthesis of ( E )-styrylflavones through Wittig reactions, is also studied.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-0033-1340013