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Ruthenium-Catalyzed Direct N-Formylation of Lactams with Paraformaldehyde

Abstract Catalytic N-formylation of lactams was conducted with paraformaldehyde using Shvo’s catalyst. Various lactams were smoothly converted into N -formylimides without the use of a stoichiometric activating reagent.

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Bibliographic Details
Published in:Synlett 2015-05, Vol.26 (8), p.1077-1080
Main Authors: Lee, Hoseong, Kang, Byungjun, Lee, Sang-Ick, Hong, Soon Hyeok
Format: Article
Language:English
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Description
Summary:Abstract Catalytic N-formylation of lactams was conducted with paraformaldehyde using Shvo’s catalyst. Various lactams were smoothly converted into N -formylimides without the use of a stoichiometric activating reagent.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-0034-1378689