Ruthenium-Catalyzed Direct N-Formylation of Lactams with Paraformaldehyde

Abstract Catalytic N-formylation of lactams was conducted with paraformaldehyde using Shvo’s catalyst. Various lactams were smoothly converted into N -formylimides without the use of a stoichiometric activating reagent.

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Published in:Synlett 2015-05, Vol.26 (8), p.1077-1080
Main Authors: Lee, Hoseong, Kang, Byungjun, Lee, Sang-Ick, Hong, Soon Hyeok
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container_end_page 1080
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container_title Synlett
container_volume 26
creator Lee, Hoseong
Kang, Byungjun
Lee, Sang-Ick
Hong, Soon Hyeok
description Abstract Catalytic N-formylation of lactams was conducted with paraformaldehyde using Shvo’s catalyst. Various lactams were smoothly converted into N -formylimides without the use of a stoichiometric activating reagent.
doi_str_mv 10.1055/s-0034-1378689
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title Ruthenium-Catalyzed Direct N-Formylation of Lactams with Paraformaldehyde
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