Enantioselective Copper-Catalyzed Reductive Coupling of Vinylazaarenes with N-Boc Aldimines

Abstract The diastereo- and enantioselective reductive coupling of vinylazaarenes with N -Boc aldimines is described. The reactions proceed using chiral copper–bisphosphine complexes in the presence of TMDS as a hydride source to give reductive coupling products in moderate to high enantioselectivit...

Full description

Saved in:
Bibliographic Details
Published in:Synlett 2014-11, Vol.26 (3), p.350-351
Main Authors: Choi, Bonnie, Saxena, Aakarsh, Smith, Joshua J., Churchill, Gwydion H., Lam, Hon Wai
Format: Article
Language:English
Subjects:
cluster
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract The diastereo- and enantioselective reductive coupling of vinylazaarenes with N -Boc aldimines is described. The reactions proceed using chiral copper–bisphosphine complexes in the presence of TMDS as a hydride source to give reductive coupling products in moderate to high enantioselectivities.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-0034-1379548