Recent Advances in the Synthesis of Sulfones

Abstract Sulfones are versatile intermediates in organic synthesis and important building blocks in the construction of biological active molecules or functional materials. This review provides a summary of recent developments in the synthesis of sulfones. 1 Introduction 2 Classical Methods and Vari...

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Published in:Synthesis (Stuttgart) 2016-07, Vol.48 (13), p.1939-1973
Main Authors: Liu, Nai-Wei, Liang, Shuai, Manolikakes, Georg
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Language:English
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container_end_page 1973
container_issue 13
container_start_page 1939
container_title Synthesis (Stuttgart)
container_volume 48
creator Liu, Nai-Wei
Liang, Shuai
Manolikakes, Georg
description Abstract Sulfones are versatile intermediates in organic synthesis and important building blocks in the construction of biological active molecules or functional materials. This review provides a summary of recent developments in the synthesis of sulfones. 1 Introduction 2 Classical Methods and Variants 2.1 Oxidation of Sulfides 2.2 Aromatic Sulfonylation 2.3 Alkylation/Arylation of Sulfinates 2.4 Addition to Alkenes and Alkynes 2.5 Miscellaneous Methods 3 Metal-Catalyzed Coupling Reactions 4 Sulfone Synthesis by C–H Functionalization 5 Sulfur Dioxide Based Three-Component Approaches 6 Biological Synthesis of Sulfones 7 Conclusion
doi_str_mv 10.1055/s-0035-1560444
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title Recent Advances in the Synthesis of Sulfones
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