Benzoyl Shift: A New Approach to Reverse Regioselectivity in the Monoprotection of vic-Diols

Abstract The benzoyl shift in monoprotected vic -diols is described. Triggered under mild conditions, this transformation allows regioselective protection of the least acidic hydroxyl function of an activated vic -diol.

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Bibliographic Details
Published in:Synlett 2016-09, Vol.27 (15), p.2205-2208
Main Authors: de la Torre, Aurélien, Oger, Camille, Bultel-Poncé, Valérie, Durand, Thierry, Galano, Jean-Marie
Format: Article
Language:English
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Description
Summary:Abstract The benzoyl shift in monoprotected vic -diols is described. Triggered under mild conditions, this transformation allows regioselective protection of the least acidic hydroxyl function of an activated vic -diol.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-0035-1561496