Phenol Oxidative Dearomatization of Modified Nucleoside Templates: A Simple Access to the C7-Spiroannulated Octosyl Acid Framework

Abstract Phenol oxidative dearomatization and cyclization has been executed successfully on nucleoside templates to synthesize C7-spiroannulated perhydrofuropyran nucleosides and C6-spiroannulated perhydrofurofuran nucleosides as novel analogues of octosyl acid and related peptidyl nucleosides.

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Bibliographic Details
Published in:Synthesis (Stuttgart) 2017-09, Vol.49 (18), p.4221-4228
Main Authors: Mullapudi, Venkannababu, Bhogade, Ravindra B., Deshpande, Mukund V., Ramana, Chepuri V.
Format: Article
Language:English
Subjects:
special topic
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Summary:Abstract Phenol oxidative dearomatization and cyclization has been executed successfully on nucleoside templates to synthesize C7-spiroannulated perhydrofuropyran nucleosides and C6-spiroannulated perhydrofurofuran nucleosides as novel analogues of octosyl acid and related peptidyl nucleosides.
ISSN:0039-7881
1437-210X
DOI:10.1055/s-0036-1588543