Asymmetric Michael Reactions Using Tartrate-based Magnesium Catalysts

Abstract Catalysts derived from a combination of dialkyl tartrates and dibutylmagnesium are effective for the asymmetric Michael addition of dibenzyl malonate to enones with ee’s up to 58%.

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Bibliographic Details
Published in:Synlett 2002-10, Vol.2002 (10), p.1700-1702
Main Authors: MacCulloch, Alasdair C., Yolka, Sylvie, Jackson, Richard F.
Format: Article
Language:English
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Description
Summary:Abstract Catalysts derived from a combination of dialkyl tartrates and dibutylmagnesium are effective for the asymmetric Michael addition of dibenzyl malonate to enones with ee’s up to 58%.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-2002-34244