An Efficient Synthesis of Trihydroxy Quinolizidine Alkaloids Using Ring-Closing Metathesis

Abstract The sequential C- and N-allylation of D-glucose-derived nitrone 2 provides the required diene functionality with nitrogen linker that was used in ring-closing metathesis pathway in the synthesis of quinolizidine alkaloids 1A and 1B.

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Bibliographic Details
Published in:Synlett 2004-07, Vol.2004 (9), p.1549-1552
Main Authors: Dhavale, Dilip D., Jachak, Santosh M., Karche, Navnath P., Trombini, Claudio
Format: Article
Language:English
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Description
Summary:Abstract The sequential C- and N-allylation of D-glucose-derived nitrone 2 provides the required diene functionality with nitrogen linker that was used in ring-closing metathesis pathway in the synthesis of quinolizidine alkaloids 1A and 1B.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-2004-829538