Total Synthesis of (-)-Neoechinulin A

Abstract A total synthesis of neoechinulin A was accomplished with high enantiomeric excess. Our total synthesis of neoechinulin A established the absolute configuration of natural neoechinulin A. The synthetic route features aldol condensation of a 3-formyl indole derivative and intramolecular cycl...

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Bibliographic Details
Published in:Synlett 2006-03, Vol.2006 (5), p.0677-0680
Main Authors: Aoki, Toshiaki, Kamisuki, Shinji, Kimoto, Masaaki, Ohnishi, Kensuke, Takakusagi, Yoichi, Kuramochi, Kouji, Takeda, Yoshifumi, Nakazaki, Atsuo, Kuroiwa, Kenji, Ohuchi, Takashi, Sugawara, Fumio, Arai, Takao, Kobayashi, Susumu
Format: Article
Language:English
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Summary:Abstract A total synthesis of neoechinulin A was accomplished with high enantiomeric excess. Our total synthesis of neoechinulin A established the absolute configuration of natural neoechinulin A. The synthetic route features aldol condensation of a 3-formyl indole derivative and intramolecular cyclization.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-2006-933113