Chlorotrimethylsilane-Mediated Friedländer Synthesis of Polysubstituted Quinolines

Abstract New convenient conditions for the Friedländer synthesis of quinolines are described. Polysubstituted quinolines were readily prepared using chlorotrimethylsilane as a promoter and water-acceptor agent.

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Bibliographic Details
Published in:Synthesis (Stuttgart) 2007-04, Vol.2007 (8), p.1214-1224
Main Authors: Ryabukhin, Sergey V., Volochnyuk, Dmitriy M., Plaskon, Andrey S., Naumchik, Vasiliy S., Tolmachev, Andrei A.
Format: Article
Language:English
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Description
Summary:Abstract New convenient conditions for the Friedländer synthesis of quinolines are described. Polysubstituted quinolines were readily prepared using chlorotrimethylsilane as a promoter and water-acceptor agent.
ISSN:0039-7881
1437-210X
DOI:10.1055/s-2007-966003