Synthesis of the C19-C34 Segment of Amphidinolide C

Abstract The synthesis of the C19-C34 segment of amphidinolide C is described. The key steps include the Mioskowski’s Lewis acid catalyzed epoxide opening with the alcohol, ring-closing metathesis, Wittig reaction, and Nozaki-Hiyama-Kishi coupling reaction.

Saved in:
Bibliographic Details
Published in:Synlett 2007-03, Vol.2007 (4), p.0567-0570
Main Authors: Mohapatra, Debendra K., Rahaman, Hasibur, Chorghade, Mukund S., Gurjar, Mukund K.
Format: Article
Language:English
Subjects:
letter
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract The synthesis of the C19-C34 segment of amphidinolide C is described. The key steps include the Mioskowski’s Lewis acid catalyzed epoxide opening with the alcohol, ring-closing metathesis, Wittig reaction, and Nozaki-Hiyama-Kishi coupling reaction.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-2007-967968